Wepresent VIXEN– a technique that succinctly summarizes in text the visual differences between a pair of images in order to highlight any content manipulation present. Our proposed network linearly maps image features in a pairwise manner, constructing a soft prompt for a pretrained large language model. We address the challenge of low volume of training data and lack of manipulation variety in existing image difference captioning (IDC) datasets by training on synthetically manipulated images from the recent InstructPix2Pix dataset generated via prompt-to-prompt editing framework. We augment this dataset with change summaries produced via GPT3. We show that VIXEN produces state-of-the-art, comprehensible difference captions for diverse image contents and edit types, offering a potential mitigation against misinformation disseminated via manipulated image content.